Neuroligin 1 antibody (AA 621-720) (HRP)

Catalog No. ABIN7091460

This Rabbit Polyclonal antibody specifically detects Neuroligin 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Neuroligin 1 antibody (AA 621-720) (HRP) (ABIN7091460)

Target: Neuroligin 1 (NLGN1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroligin 1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Neuroligin 1 Antibody (HRP)

Binding Specificity: AA 621-720

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neuroligin 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for Neuroligin 1

Target: Neuroligin 1 (NLGN1)

Alternative Name: Neuroligin 1

Background:

Synonyms: NLG 1, KIAA1070, MGC45115, NLG1, Neuroligin-1, NLGN1, NLGN1_HUMAN.

Background: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Subunit : Interacts with NRXN1, NRXN2 and NRXN3. Interacts with NLGN3. Interacts with AIP1 and PDZRN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with GOPC.

Gene ID: 22871

UniProt: Q8N2Q7

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis