NRF1 antibody

Catalog No. ABIN7091482

The Mouse Monoclonal anti-NRF1 antibody has been validated for WB, IF and ICC. It is suitable to detect NRF1 in samples from Human.

Quick Overview for NRF1 antibody (ABIN7091482)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NRF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: A11D10

Product Details anti-NRF1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human NRF1

Isotype: IgG2b, kappa

Application Details

Application Notes: WB 1:300-5000
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Alternative Name: NRF1

Background:

Synonyms: erythroid derived 2, like 1, Locus control region factor 1, Locus control region-factor 1, NF-E2-related factor 1, NF2L1_HUMAN, NFE2 related factor 1, NFE2-related factor 1, NFE2L1, NRF-1, NRF 1, Nuclear factor, Nuclear factor erythroid 2-related factor 1, Nuclear factor erythroid derived 2 like 1, TCF-11, TCF11, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR F1, Transcription factor LCR-F1.

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

Gene ID: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha