RAB23 antibody

Catalog No. ABIN7091627

This anti-RAB23 antibody is a Mouse Monoclonal antibody detecting RAB23 in WB, ELISA and IF. Suitable for Human.

Quick Overview for RAB23 antibody (ABIN7091627)

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: G6S4

Product Details anti-RAB23 Antibody

Predicted Reactivity: Human,Mouse

Immunogen: Recombinant human RAB23 (Fragment) (His-tagged).

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IF()

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RAB23

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Alternative Name: RAB23

Background:

Synonyms: DKFZp781H0695, HSPC137, MGC8900, Rab 23, RAB family small GTP binding protein RAB 23, RAB23, member RAS oncogene family, RAB23_HUMAN, Ras related protein Rab 23, Ras-related protein Rab-23.

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Gene ID: 51715

UniProt: Q9ULC3

Pathways: Tube Formation