ROCK2 antibody

Catalog No. ABIN7091645

The Mouse Monoclonal anti-ROCK2 antibody (Clone E2C11) (ABIN7091645) specifically detects ROCK2 in WB. The antibody is reactive with Human samples.

Quick Overview for ROCK2 antibody (ABIN7091645)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ROCK2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: E2C11

Product Details anti-ROCK2 Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ROCK2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Alternative Name: ROCK2

Background:

Synonyms: p164 ROCK 2, p164 ROCK-2, Rho associated coiled coil containing protein kinase 2, Rho associated protein kinase 2, Rho kinase 2, ROCK 2, Rock II, Rock2m, ROK alpha, ROKalpha, coiled-coil-containing protein kinase 2, KIAA0619, Rho associated, coiled coil containing protein kinase II, Rho-associated, Rho-associated protein kinase 2, Rock2, ROCK2_HUMAN.

Background: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008].

Gene ID: 9475

UniProt: O75116

Pathways: Microtubule Dynamics, WNT Signaling, Tube Formation