TPX2 antibody (AA 1-531)

Catalog No. ABIN7091748

This Mouse Monoclonal antibody specifically detects TPX2 in WB. It exhibits reactivity toward Human.

Quick Overview for TPX2 antibody (AA 1-531) (ABIN7091748)

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TPX2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: C3A12

Product Details anti-TPX2 Antibody

Binding Specificity: AA 1-531

Predicted Reactivity: Human

Immunogen: Recombinant human TPX2 between 1-531 amino acids.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Alternative Name: TPX2

Background:

Synonyms: C20ORF1, C20orf2, Chromosome 20 Open Reading Frame 1, Differentially expressed in cancerous and non-cancerous lung cells 2, Differentially expressed in cancerous and noncancerous lung cells 2, Differentially expressed in lung cells 2, Differentially expressed in lung cells, DIL 2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA 519, HCA519, HCTP 4, HCTP4, Hepatocellular carcinoma associated antigen 519, Hepatocellular carcinoma-associated antigen 519, p100, Preferentially expressed in colorectal cancer, Protein FLS353, REPP 86, repp86, Restricted expression proliferation associated protein 100, Restricted expression proliferation-associated protein 100, Targeting protein for XKLP2, TPX 2, TPX2 microtubule associated homolog, TPX2 microtubule associated protein homolog, TPX2_HUMAN.

Background: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Gene ID: 22974

UniProt: Q9ULW0