VTA1 antibody (AA 221-306)

Catalog No. ABIN7091817

This Rabbit Polyclonal antibody specifically detects VTA1 in IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for VTA1 antibody (AA 221-306) (ABIN7091817)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VTA1 Antibody

Binding Specificity: AA 221-306

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIP5

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: LIP5

Background:

Synonyms: C6orf55 Chromosome 6 open reading frame 55, Dopamine responsive protein DRG 1, Dopamine-responsive gene 1 protein, DRG 1, DRG-1, DRG1, Homolog of mouse SKD1 binding protein 1, HSPC228, LIP5, LYST interacting protein 5, LYST-interacting protein 5, My012, SBP1, SKD1 binding protein 1, SKD1-binding protein 1, Vacuolar protein sorting-associated protein VTA1 homolog, Vps20 associated 1 homolog (S. cerevisiae), VTA1, VTA1_HUMAN

Background: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.

Gene ID: 51534

UniProt: Q9NP79