XIAP antibody

Catalog No. ABIN7091829

This Mouse Monoclonal antibody specifically detects XIAP in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for XIAP antibody (ABIN7091829)

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XIAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: D1G6

Product Details anti-XIAP Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human XIAP.

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for XIAP

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Alternative Name: XIAP

Background:

Synonyms: X-linked Inhibitor of Apoptosis Protein, RIAP-3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, Inhibitor of apoptosis protein 3, X-linked IAP, IAP-like protein, HILP, BIRC4, HILP, XLP2, ILP1, Xiap, MIHA, hILP, IAP3, API3, XIAP_HUMAN, ILP, hILP, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein.

Background: Apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. Inhibitor of caspase-3, -7 and -9. Mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B.

Gene ID: 331

UniProt: P98170

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis