CD133 Antigen (AA 836-865) antibody (Biotin)
This Rabbit Polyclonal antibody specifically detects in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN7091859
Quick Overview for CD133 Antigen (AA 836-865) antibody (Biotin) (ABIN7091859)
Target
CD133 Antigen
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Application
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Binding Specificity
- AA 836-865
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Cross-Reactivity
- Human, Mouse
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Predicted Reactivity
- Rat,Fruit Fly
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CD133 antigen
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C for 12 months.
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Expiry Date
- 12 months
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- CD133 Antigen
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Background
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Synonyms: AC133, Antigen AC133, Hematopoietic stem cell antigen, hProminin, PROM1, Prominin I, Prominin like protein 1 precursor, Prominin mouse like 1, prominin1, PROML1, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, PROM1_HUMAN.
Background: Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
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Gene ID
- 8842
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UniProt
- O43490
Target
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