ICOSLG antibody (AA 19-256) (Biotin)

Catalog No. ABIN7093042

The Rabbit Monoclonal anti-ICOSLG antibody is suitable to detect ICOSLG in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for ICOSLG antibody (AA 19-256) (Biotin) (ABIN7093042)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICOSLG antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: DM97

Product Details anti-ICOSLG Antibody (Biotin)

Binding Specificity: AA 19-256

Purpose: Biotinylated Anti-B7-H2 antibody(DM97), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human B7-H2 (Asp19-Thr256) (ABIN6961102) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: B7-H2

Background: Synonyms:ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand
Description:Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

Molecular Weight: 33.3kDa

Gene ID: 23308

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation