CXCL13 antibody (AA 23-109)

Catalog No. ABIN706691

The Rabbit Polyclonal anti-CXCL13 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect CXCL13 in samples from Mouse and Rat. There are 3+ publications available.

Quick Overview for CXCL13 antibody (AA 23-109) (ABIN706691)

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CXCL13 Antibody

Binding Specificity: AA 23-109

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL13/BCA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL13 antibody (ABIN706691)

Doloff, Veiseh, Vegas, Tam, Farah, Ma, Li, Bader, Chiu, Sadraei, Aresta-Dasilva, Griffin, Jhunjhunwala, Webber, Siebert, Tang, Chen, Langan, Dholokia, Thakrar, Qi, Oberholzer, Greiner, Langer et al.: "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. ..." in: Nature materials, Vol. 16, Issue 6, pp. 671-680, (2017) (PubMed).

Wang, Cao, Li, Zhang: "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." in: Cytokine, Vol. 88, pp. 232-240, (2016) (PubMed).

Siepert, Brösel, Vogt, Ahrlich, Schmitt-Knosalla, Loddenkemper, Kühl, Baumgrass, Gerstmayer, Tomiuk, Tiedge, Viklický, Brabcova, Nizze, Lehmann, Volk, Sawitzki: "Mechanisms and Rescue Strategies of Calcineurin Inhibitor Mediated Tolerance Abrogation Induced by Anti-CD4 mAb Treatment." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, (2013) (PubMed).

Target Details for CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Alternative Name: CXCL13/BCA1

Background:

Synonyms: BLC, Angie, BCA-1, BLR1L, ANGIE2, Scyb13, 4631412M8Rik, C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13

Background: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Gene ID: 55985

UniProt: O55038