TUBB3 antibody (AA 401-450)

Catalog No. ABIN706736

The Rabbit Polyclonal anti-TUBB3 antibody has been validated for WB, ELISA, FACS, IHC (p), ICC, IF (p), IHC (fro) and IF (cc). It is suitable to detect TUBB3 in samples from Human, Mouse, Rat and Dog. There is 1 publication available.

Quick Overview for TUBB3 antibody (AA 401-450) (ABIN706736)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-TUBB3 Antibody

Binding Specificity: AA 401-450

Cross-Reactivity: Dog, Human, Mouse, Rat

Predicted Reactivity: Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neuron specific beta III Tubulin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TUBB3 antibody (ABIN706736)

Song, Yang, Wang, Zhu, Zhou, Yin, Yao, Zhao: "Overexpression of BAT3 alleviates prion protein fragment PrP106-126-induced neuronal apoptosis." in: CNS neuroscience & therapeutics, Vol. 20, Issue 8, pp. 737-47, (2014) (PubMed).

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: beta 3 Tubulin

Background:

Synonyms: CDCBM, FEOM3, TUBB4, CDCBM1, CFEOM3, beta-4, CFEOM3A, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3

Background: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

Gene ID: 10381

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase