ACADVL antibody (AA 534-578)

Catalog No. ABIN7111265

The Rabbit Polyclonal anti-ACADVL antibody has been validated for WB, ELISA and IHC. It is suitable to detect ACADVL in samples from Human, Rat and Mouse.

Quick Overview for ACADVL antibody (AA 534-578) (ABIN7111265)

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADVL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ACADVL Antibody

Binding Specificity: AA 534-578

Purpose: ACADVL antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 534-578aa

Immunogen: acyl-Coenzyme A dehydrogenase, very long chain

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ACADVL

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Alternative Name: ACADVL

Background:

Synonyms: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD)|ACADVL|VLCAD

Background: Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71- kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.

Molecular Weight: 48 kDa, 68-73 kDa

Gene ID: 37

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process