AP4M1 antibody

Catalog No. ABIN7111317

The Rabbit Polyclonal anti-AP4M1 antibody (ABIN7111317) specifically detects AP4M1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AP4M1 antibody (ABIN7111317)

Target: AP4M1 (Ap4m1) (Adaptor-Related Protein Complex 4, mu 1 Subunit (Ap4m1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP4M1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AP4M1 Antibody

Purpose: AP4M1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: adaptor-related protein complex 4, mu 1 subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AP4M1

Target: AP4M1 (Ap4m1) (Adaptor-Related Protein Complex 4, mu 1 Subunit (Ap4m1))

Alternative Name: AP4M1

Background:

Synonyms: AP-4 complex subunit mu-1|AP-4 adaptor complex mu subunit|Adaptor-related protein complex 4 subunit mu-1|Mu subunit of AP-4|Mu-adaptin-related protein 2 (mu-ARP2)|Mu4-adaptin (mu4)|AP4M1|MUARP2

Background: Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.

Molecular Weight: 50-55 kDa

Gene ID: 9179

UniProt: O00189