ADIPOQ antibody (AA 1-244)

Catalog No. ABIN7111358

The Mouse Monoclonal anti-ADIPOQ antibody has been validated for WB and ELISA. It is suitable to detect ADIPOQ in samples from Human and Mouse.

Quick Overview for ADIPOQ antibody (AA 1-244) (ABIN7111358)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADIPOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6E1

Product Details anti-ADIPOQ Antibody

Binding Specificity: AA 1-244

Purpose: ADIPOQ antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-244aa

Immunogen: adiponectin, C1Q and collagen domain containing

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: ADIPOQ

Background:

Synonyms: Adiponectin|30 kDa adipocyte complement-related protein|Adipocyte complement-related 30 kDa protein (ACRP30)|Adipocyte, C1q and collagen domain-containing protein|Adipose most abundant gene transcript 1 protein (apM-1)|Gelatin-binding protein|ADIPOQ|ACDC|ACRP30|APM1|GBP28

Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Molecular Weight: 26 kDa

Gene ID: 9370

UniProt: Q15848