ALDOC antibody

Catalog No. ABIN7111475

The Rabbit Polyclonal anti-ALDOC antibody has been validated for WB, ELISA and IF. It is suitable to detect ALDOC in samples from Human, Mouse and Rat.

Quick Overview for ALDOC antibody (ABIN7111475)

Target: ALDOC (Aldolase C, Fructose-Bisphosphate (ALDOC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ALDOC Antibody

Purpose: ALDOC antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: aldolase C, fructose-bisphosphate

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ALDOC

Target: ALDOC (Aldolase C, Fructose-Bisphosphate (ALDOC))

Alternative Name: ALDOC

Background:

Synonyms: Fructose-bisphosphate aldolase C|Brain-type aldolase|ALDOC|ALDC

Background: Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Molecular Weight: 39 kDa

Gene ID: 230

UniProt: P09972