The Rabbit Polyclonal anti-ALDOC antibody has been validated for WB, ELISA and IF. It is suitable to detect ALDOC in samples from Human, Mouse and Rat.
ALDOC
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB14983
unconjugated
Application Notes
WB: 1:500-1:5000, IF: 1:10-1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
ALDOC
(Aldolase C, Fructose-Bisphosphate (ALDOC))
Alternative Name
Aldolase C
Background
Synonyms:ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C Background:Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).