ALKBH4 antibody

Catalog No. ABIN7111482

The Rabbit Polyclonal anti-ALKBH4 antibody (ABIN7111482) specifically detects ALKBH4 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ALKBH4 antibody (ABIN7111482)

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ALKBH4 Antibody

Purpose: ALKBH4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: alkB, alkylation repair homolog 4(E. coli)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ALKBH4

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Alternative Name: ALKBH4

Background:

Synonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|Alkylated DNA repair protein alkB homolog 4|DNA N6-methyl adenine demethylase ALKBH4|Lysine-specific demethylase ALKBH4|ALKBH4|ABH4

Background: Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84'(K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

Molecular Weight: 34 kDa

Gene ID: 54784

UniProt: Q9NXW9