Anoctamin 2 antibody

Catalog No. ABIN7111632

This anti-Anoctamin 2 antibody is a Rabbit Polyclonal antibody detecting Anoctamin 2 in WB, ELISA, IHC, IF and IP. Suitable for Human, Mouse and Rat.

Quick Overview for Anoctamin 2 antibody (ABIN7111632)

Target: Anoctamin 2 (ANO2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Anoctamin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Anoctamin 2 Antibody

Purpose: ANO2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: anoctamin 2

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000, IHC: 1:20-1:200, IF: 1:10-1:100, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Anoctamin 2

Target: Anoctamin 2 (ANO2)

Alternative Name: ANO2

Background:

Synonyms: Anoctamin-2|Transmembrane protein 16B|ANO2|C12orf3|TMEM16B

Background: Calcium-activated chloride channel(CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors(OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

Molecular Weight: 114 kDa

Gene ID: 57101

UniProt: Q9NQ90