ALOX15B antibody (AA 1-200)

Catalog No. ABIN7111694

The Rabbit Polyclonal anti-ALOX15B antibody is suitable to detect ALOX15B in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for ALOX15B antibody (AA 1-200) (ABIN7111694)

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX15B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ALOX15B Antibody

Binding Specificity: AA 1-200

Purpose: ALOX15B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-200aa

Immunogen: arachidonate 15-lipoxygenase, type B

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ALOX15B

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Alternative Name: ALOX15B

Background:

Synonyms: Polyunsaturated fatty acid lipoxygenase ALOX15B|15-lipoxygenase 2 (15-LOX-2)|Arachidonate 15-lipoxygenase B (15-LOX-B)|Arachidonate 15-lipoxygenase type II|Linoleate 13-lipoxygenase 15-LOb|ALOX15B

Background: In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.

Molecular Weight: 76 kDa

UniProt: O15296