Liver Arginase antibody

Catalog No. ABIN7111709

The Rabbit Polyclonal anti-Liver Arginase antibody has been validated for WB, ELISA, IHC, FACS, IF and IP. It is suitable to detect Liver Arginase in samples from Human, Rat and Mouse.

Quick Overview for Liver Arginase antibody (ABIN7111709)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Liver Arginase Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: arginase, liver

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: liver Arginase

Background: Synonyms:ARG1, Arginase 1, liver Arginase, Liver type arginase Background:Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

Molecular Weight: 35 kDa

Gene ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin