AGO2 antibody (AA 620-859)

Catalog No. ABIN7111718

The Rabbit Polyclonal anti-AGO2 antibody is suitable to detect AGO2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for AGO2 antibody (AA 620-859) (ABIN7111718)

Target: AGO2 (Argonaute 2 (AGO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-AGO2 Antibody

Binding Specificity: AA 620-859

Purpose: AGO2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 620-859aa

Immunogen: eukaryotic translation initiation factor 2C, 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:1000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AGO2

Target: AGO2 (Argonaute 2 (AGO2))

Alternative Name: AGO2

Background:

Synonyms: Protein argonaute-2 (Argonaute2, hAgo2)|Argonaute RISC catalytic component 2|Eukaryotic translation initiation factor 2C 2 (eIF-2C 2, eIF2C 2)|PAZ Piwi domain protein (PPD)|Protein slicer|AGO2|EIF2C2

Background: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 100 kDa

Gene ID: 27161

UniProt: Q9UKV8

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization