AKNA antibody

Catalog No. ABIN7111768

This Rabbit Polyclonal antibody specifically detects AKNA in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for AKNA antibody (ABIN7111768)

Target: AKNA (AT-Hook Transcription Factor (AKNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKNA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AKNA Antibody

Purpose: AKNA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: AT-hook transcription factor

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AKNA

Target: AKNA (AT-Hook Transcription Factor (AKNA))

Alternative Name: AKNA

Background:

Synonyms: Microtubule organization protein AKNA|AT-hook-containing transcription factor|AKNA|KIAA1968

Background: AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)

Molecular Weight: 65-70 kDa

Gene ID: 80709

UniProt: Q7Z591