CAPZB antibody

Catalog No. ABIN7112267

The Rabbit Polyclonal anti-CAPZB antibody has been validated for WB and ELISA. It is suitable to detect CAPZB in samples from Human and Mouse.

Quick Overview for CAPZB antibody (ABIN7112267)

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CAPZB Antibody

Purpose: CAPZB antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: capping protein(actin filament) muscle Z-line, beta

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CAPZB

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Alternative Name: CAPZB

Background:

Synonyms: F-actin-capping protein subunit beta|CapZ beta|CAPZB

Background: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins(such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Molecular Weight: 30-31 kDa

Gene ID: 832

UniProt: P47756

Pathways: Regulation of Actin Filament Polymerization