CHST3 antibody

Catalog No. ABIN7112276

The Rabbit Polyclonal anti-CHST3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect CHST3 in samples from Human, Mouse and Rat.

Quick Overview for CHST3 antibody (ABIN7112276)

Target: CHST3 (Carbohydrate (Chondroitin 6) Sulfotransferase 3 (CHST3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CHST3 Antibody

Purpose: CHST3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: carbohydrate(chondroitin 6) sulfotransferase 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CHST3

Target: CHST3 (Carbohydrate (Chondroitin 6) Sulfotransferase 3 (CHST3))

Alternative Name: CHST3

Background:

Synonyms: Carbohydrate sulfotransferase 3|Chondroitin 6-O-sulfotransferase 1 (C6ST-1)|Chondroitin 6-sulfotransferase (C6ST)|Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 (GST-0)|CHST3

Background: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate(PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine(GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine(sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.

Molecular Weight: 67 kDa

Gene ID: 9469

UniProt: Q7LGC8

Pathways: Glycosaminoglycan Metabolic Process