CD63 antibody (AA 104-209)

Catalog No. ABIN7112507

The Rabbit Polyclonal anti-CD63 antibody is suitable to detect CD63 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for CD63 antibody (AA 104-209) (ABIN7112507)

Target: CD63

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD63 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CD63 Antibody

Binding Specificity: AA 104-209

Purpose: CD63 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 104-209aa

Immunogen: CD63 molecule

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CD63

Target: CD63

Alternative Name: CD63

Background:

Synonyms: CD63 antigen|Granulophysin|Lysosomal-associated membrane protein 3 (LAMP-3)|Lysosome integral membrane protein 1 (Limp1)|Melanoma-associated antigen ME491|OMA81H|Ocular melanoma-associated antigen|Tetraspanin-30 (Tspan-30)|CD63|MLA1|TSPAN30

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Molecular Weight: 26-60 kDa

Gene ID: 967

UniProt: P08962