COPZ1 antibody

Catalog No. ABIN7112913

This anti-COPZ1 antibody is a Rabbit Polyclonal antibody detecting COPZ1 in WB and ELISA. Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for COPZ1 antibody (ABIN7112913)

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPZ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COPZ1 Antibody

Purpose: COPZ1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coatomer protein complex, subunit zeta 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for COPZ1

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Alternative Name: COPZ1

Background:

Synonyms: Coatomer subunit zeta-1|Zeta-1-coat protein (Zeta-1 COP)|COPZ1|COPZ

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors(ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Molecular Weight: 20 kDa

Gene ID: 22818

UniProt: P61923