CCDC40 antibody

Catalog No. ABIN7112946

This anti-CCDC40 antibody is a Rabbit Polyclonal antibody detecting CCDC40 in ELISA and WB. Suitable for Human.

Quick Overview for CCDC40 antibody (ABIN7112946)

Target: CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC40 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CCDC40 Antibody

Purpose: CCDC40 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coiled-coil domain containing 40

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CCDC40

Target: CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))

Alternative Name: CCDC40

Background:

Synonyms: Coiled-coil domain-containing protein 40|CCDC40|KIAA1640

Background: Required for assembly of dynein regulatory complex(DRC) and inner dynein arm(IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella(PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer(nm) repeat length and arrangements of components in cilia and flagella(By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39(PubMed:21131974).

Molecular Weight: 90-100 kDa

Gene ID: 55036

UniProt: Q4G0X9