CCDC53 antibody

Catalog No. ABIN7112952

The Rabbit Polyclonal anti-CCDC53 antibody (ABIN7112952) specifically detects CCDC53 in ELISA, IHC and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for CCDC53 antibody (ABIN7112952)

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC53 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CCDC53 Antibody

Purpose: WASHC3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coiled-coil domain containing 53

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CCDC53

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Alternative Name: WASHC3

Background:

Synonyms: WASH complex subunit 3|Coiled-coil domain-containing protein 53|WASHC3

Background: Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor(NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting(PubMed:19922875, PubMed:20498093).

Gene ID: 51019

UniProt: Q9Y3C0