CUX1 antibody

Catalog No. ABIN7113121

This Rabbit Polyclonal antibody specifically detects CUX1 in WB, ELISA, IF, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CUX1 antibody (ABIN7113121)

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-CUX1 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: cut-like homeobox 1

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:3000, IP:1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1

Background: Synonyms:CASP, CCAAT displacement protein, CDP, CDP/Cut, CDP1, Clox, COY1, cut like homeobox 1, CUTL1, CUX, Cux/CDP, CUX1, GOLIM6, Homeobox protein cut like 1, Homeobox protein cux 1, Nbla10317, p100, p110, p200, p75 Background:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).

Molecular Weight: 80 kDa

Gene ID: 1523

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process