CDO1 antibody

Catalog No. ABIN7113202

This Rabbit Polyclonal antibody specifically detects CDO1 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDO1 antibody (ABIN7113202)

Target: CDO1 (Cysteine Dioxygenase, Type I (CDO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-CDO1 Antibody

Purpose: CDO1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: cysteine dioxygenase, type I

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CDO1

Target: CDO1 (Cysteine Dioxygenase, Type I (CDO1))

Alternative Name: CDO1

Background:

Synonyms: Cysteine dioxygenase type 1|Cysteine dioxygenase type I (CDO, CDO-I)|CDO1

Background: CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid(3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase(CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO(23 kDa, 25 kDa, and 68 kDa) have been claimed based upon separation and detection using S

Molecular Weight: 23 kDa

UniProt: Q16878