DAB2IP antibody

Catalog No. ABIN7113309

The Rabbit Polyclonal anti-DAB2IP antibody (ABIN7113309) specifically detects DAB2IP in WB, ELISA and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for DAB2IP antibody (ABIN7113309)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2IP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-DAB2IP Antibody

Purpose: DAB2IP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: DAB2 interacting protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP

Background:

Synonyms: Disabled homolog 2-interacting protein (DAB2 interaction protein, DAB2-interacting protein)|ASK-interacting protein 1 (AIP-1)|DOC-2/DAB-2 interactive protein|DAB2IP|AF9Q34|AIP1|KIAA1743

Background: Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control, reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor(TNF), interferon(IFN) or lipopolysaccharide(LPS).

Molecular Weight: 130 kDa

Gene ID: 153090

UniProt: Q5VWQ8

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation