DDRGK1 antibody
Quick Overview for DDRGK1 antibody (ABIN7113329)
Target
See all DDRGK1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- DDRGK1 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- DDRGK domain containing 1
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- DDRGK1 (DDRGK Domain Containing 1 (DDRGK1))
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Alternative Name
- DDRGK1
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Background
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Synonyms: DDRGK domain-containing protein 1|Dashurin|UFM1-binding and PCI domain-containing protein 1|DDRGK1|C20orf116|UFBP1
Background: Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription(PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B(PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress(By similarity).
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Molecular Weight
- 36-46 kDa
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Gene ID
- 65992
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UniProt
- Q96HY6
Target
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