DDRGK1 antibody

Catalog No. ABIN7113329

The Rabbit Polyclonal anti-DDRGK1 antibody is suitable to detect DDRGK1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for DDRGK1 antibody (ABIN7113329)

Target: DDRGK1 (DDRGK Domain Containing 1 (DDRGK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDRGK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DDRGK1 Antibody

Purpose: DDRGK1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: DDRGK domain containing 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DDRGK1

Target: DDRGK1 (DDRGK Domain Containing 1 (DDRGK1))

Alternative Name: DDRGK1

Background:

Synonyms: DDRGK domain-containing protein 1|Dashurin|UFM1-binding and PCI domain-containing protein 1|DDRGK1|C20orf116|UFBP1

Background: Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription(PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B(PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress(By similarity).

Molecular Weight: 36-46 kDa

Gene ID: 65992

UniProt: Q96HY6