ELOVL2 antibody

Catalog No. ABIN7113783

This anti-ELOVL2 antibody is a Rabbit Polyclonal antibody detecting ELOVL2 in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for ELOVL2 antibody (ABIN7113783)

Target: ELOVL2 (ELOVL Fatty Acid Elongase 2 (ELOVL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ELOVL2 Antibody

Purpose: ELOVL2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: elongation of very long chain fatty acids(FEN1/Elo2, SUR4/Elo3, yeast)-like 2

Isotype: IgG

Application Details

Application Notes: IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ELOVL2

Target: ELOVL2 (ELOVL Fatty Acid Elongase 2 (ELOVL2))

Alternative Name: ELOVL2

Background:

Synonyms: Very long chain fatty acid elongase 2|3-keto acyl-CoA synthase ELOVL2|ELOVL fatty acid elongase 2 (ELOVL FA elongase 2)|Elongation of very long chain fatty acids protein 2|Very long chain 3-ketoacyl-CoA synthase 2|Very long chain 3-oxoacyl-CoA synthase 2|ELOVL2|ELG3|SSC2

Background: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid(C20-and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Gene ID: 54898

UniProt: Q9NXB9