ELOVL4 antibody

Catalog No. ABIN7113784

This Rabbit Polyclonal antibody specifically detects ELOVL4 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ELOVL4 antibody (ABIN7113784)

Target: ELOVL4 (ELOVL Fatty Acid Elongase 4 (ELOVL4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ELOVL4 Antibody

Purpose: ELOVL4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: elongation of very long chain fatty acids(FEN1/Elo2, SUR4/Elo3, yeast)-like 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ELOVL4

Target: ELOVL4 (ELOVL Fatty Acid Elongase 4 (ELOVL4))

Alternative Name: ELOVL4

Background:

Synonyms: Very long chain fatty acid elongase 4|3-keto acyl-CoA synthase ELOVL4|ELOVL fatty acid elongase 4 (ELOVL FA elongase 4)|Elongation of very long chain fatty acids protein 4|Very long chain 3-ketoacyl-CoA synthase 4|Very long chain 3-oxoacyl-CoA synthase 4|ELOVL4

Background: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.

Molecular Weight: 37-40 kDa

Gene ID: 6785

UniProt: Q9GZR5