ENY2 antibody

Catalog No. ABIN7113824

The Rabbit Polyclonal anti-ENY2 antibody has been validated for ELISA. It is suitable to detect ENY2 in samples from Human, Mouse and Rat.

Quick Overview for ENY2 antibody (ABIN7113824)

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENY2 antibody is un-conjugated

Application: ELISA

Product Details anti-ENY2 Antibody

Purpose: ENY2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: enhancer of yellow 2 homolog(Drosophila)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ENY2

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Alternative Name: ENY2

Background:

Synonyms: Transcription and mRNA export factor ENY2|Enhancer of yellow 2 transcription factor homolog|ENY2

Background: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation(HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles(mRNPs) to the nuclear entrance of the nuclear pore complex(nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Gene ID: 56943

UniProt: Q9NPA8