EIF4A2 antibody (AA 110-407)

Catalog No. ABIN7113964

This Rabbit Polyclonal antibody specifically detects EIF4A2 in WB, ELISA, IHC, IF and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for EIF4A2 antibody (AA 110-407) (ABIN7113964)

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-EIF4A2 Antibody

Binding Specificity: AA 110-407

Purpose: EIF4A2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 110-407aa

Immunogen: eukaryotic translation initiation factor 4A, isoform 2

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EIF4A2

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Alternative Name: EIF4A2

Background:

Synonyms: Eukaryotic initiation factor 4A-II (eIF-4A-II, eIF4A-II)|ATP-dependent RNA helicase eIF4A-2|EIF4A2|DDX2B|EIF4F

Background: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Molecular Weight: 47 kDa

Gene ID: 1974

UniProt: Q14240