EXT2 antibody

Catalog No. ABIN7114020

The Rabbit Polyclonal anti-EXT2 antibody (ABIN7114020) specifically detects EXT2 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EXT2 antibody (ABIN7114020)

Target: EXT2 (Exostosin 2 (EXT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-EXT2 Antibody

Purpose: EXT2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: exostoses(multiple) 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EXT2

Target: EXT2 (Exostosin 2 (EXT2))

Alternative Name: EXT2

Background:

Synonyms: Exostosin-2|Exostosin glycosyltransferase 2|Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|Heparan sulfate co-polymerase subunit EXT1|Multiple exostoses protein 2|EXT2

Background: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).

Molecular Weight: 82 kDa

Gene ID: 2132

UniProt: Q93063

Pathways: Glycosaminoglycan Metabolic Process