FBXL15 antibody

Catalog No. ABIN7114035

This anti-FBXL15 antibody is a Rabbit Polyclonal antibody detecting FBXL15 in WB and ELISA. Suitable for Human.

Quick Overview for FBXL15 antibody (ABIN7114035)

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FBXL15 Antibody

Purpose: FBXL15 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: F-box and leucine-rich repeat protein 15

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FBXL15

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Alternative Name: FBXL15

Background:

Synonyms: F-box/LRR-repeat protein 15|F-box only protein 37|FBXL15|FBXO37

Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.

Molecular Weight: 33 kDa

Gene ID: 79176

UniProt: Q9H469