FNTA antibody

Catalog No. ABIN7114128

The Rabbit Polyclonal anti-FNTA antibody (ABIN7114128) specifically detects FNTA in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for FNTA antibody (ABIN7114128)

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FNTA Antibody

Purpose: FNTA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: farnesyltransferase, CAAX box, alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Alternative Name: FNTA

Background:

Synonyms: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha|CAAX farnesyltransferase subunit alpha|FTase-alpha|Ras proteins prenyltransferase subunit alpha|Type I protein geranyl-geranyltransferase subunit alpha (GGTase-I-alpha)|FNTA

Background: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.

Molecular Weight: 44 kDa

Gene ID: 2339

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling