FRMD6 antibody
Quick Overview for FRMD6 antibody (ABIN7114176)
Target
See all FRMD6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- FRMD6 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- FERM domain containing 6
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:5000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- FRMD6 (FERM Domain Containing 6 (FRMD6))
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Alternative Name
- FRMD6
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Background
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Synonyms: FERM domain-containing protein 6|Willin|FRMD6|C14orf31
Background: Willin, also known as FRMD6 or human Expanded(hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
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Molecular Weight
- 72 kDa
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UniProt
- Q96NE9
Target
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