FRMD6 antibody

Catalog No. ABIN7114176

The Rabbit Polyclonal anti-FRMD6 antibody (ABIN7114176) specifically detects FRMD6 in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FRMD6 antibody (ABIN7114176)

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRMD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FRMD6 Antibody

Purpose: FRMD6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: FERM domain containing 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FRMD6

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Alternative Name: FRMD6

Background:

Synonyms: FERM domain-containing protein 6|Willin|FRMD6|C14orf31

Background: Willin, also known as FRMD6 or human Expanded(hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.

Molecular Weight: 72 kDa

UniProt: Q96NE9