Fibromodulin antibody

Catalog No. ABIN7114223

The Rabbit Polyclonal anti-Fibromodulin antibody has been validated for WB, IHC and ELISA. It is suitable to detect Fibromodulin in samples from Human, Rat and Mouse.

Quick Overview for Fibromodulin antibody (ABIN7114223)

Target: Fibromodulin (FMOD)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Fibromodulin Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: fibromodulin

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: Fibromodulin

Background: Synonyms:fibromodulin, FM, FMOD, KSPG fibromodulin, SLRR2E Background:Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Molecular Weight: 45kDa

Gene ID: 2331

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process