FICD antibody

Catalog No. ABIN7114236

The Rabbit Polyclonal anti-FICD antibody (ABIN7114236) specifically detects FICD in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FICD antibody (ABIN7114236)

Target: FICD (FIC Domain Containing (FICD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FICD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FICD Antibody

Purpose: FICD antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: FIC domain containing

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FICD

Target: FICD (FIC Domain Containing (FICD))

Alternative Name: FICD

Background:

Synonyms: Protein adenylyltransferase FICD|AMPylator FICD|De-AMPylase FICD|FIC domain-containing protein|Huntingtin yeast partner E|Huntingtin-interacting protein 13 (HIP-13)|Huntingtin-interacting protein E|FICD|HIP13|HYPE

Background: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate(AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.

Molecular Weight: 52 kDa

Gene ID: 11153

UniProt: Q9BVA6