Fission 1 antibody

Catalog No. ABIN7114245

This anti-Fission 1 antibody is a Rabbit Polyclonal antibody detecting Fission 1 in WB, ELISA, IHC, IF and IP. Suitable for Human, Mouse and Rat.

Quick Overview for Fission 1 antibody (ABIN7114245)

Target: Fission 1 (FIS1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Fission 1 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: fission 1(mitochondrial outer membrane) homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:3000, IHC: 1:10-1:100, IF: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1

Background: Synonyms:CGI 135, FIS1, FIS1 homolog, hFis1, TPR repeat protein 11, TTC11 Background:Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1(DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Molecular Weight: 17 kDa

Gene ID: 51024

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity