GAN antibody

Catalog No. ABIN7114555

This Rabbit Polyclonal antibody specifically detects GAN in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GAN antibody (ABIN7114555)

Target: GAN (Gigaxonin (GAN))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GAN Antibody

Purpose: GAN antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: gigaxonin

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GAN

Target: GAN (Gigaxonin (GAN))

Alternative Name: GAN

Background:

Synonyms: Gigaxonin|Kelch-like protein 16|GAN|GAN1|KLHL16

Background: Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.

Molecular Weight: 68 kDa

UniProt: Q9H2C0