GLRa2 antibody

Catalog No. ABIN7114691

The Rabbit Polyclonal anti-GLRa2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect GLRa2 in samples from Rat, Human and Mouse.

Quick Overview for GLRa2 antibody (ABIN7114691)

Target: GLRa2 (Glycine Receptor, alpha 2 (GLRa2))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRa2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-GLRa2 Antibody

Purpose: GLRA2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: glycine receptor, alpha 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GLRa2

Target: GLRa2 (Glycine Receptor, alpha 2 (GLRa2))

Alternative Name: GLRA2

Background:

Synonyms: Glycine receptor subunit alpha-2|GLRA2

Background: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine(PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Plays a role in cellular responses to ethanol(PubMed:23895467).

Molecular Weight: 48 kDa

Gene ID: 2742

UniProt: P23416

Pathways: Synaptic Membrane