GM2A antibody (AA 1-193)

Catalog No. ABIN7114727

The Mouse Monoclonal anti-GM2A antibody has been validated for WB and ELISA. It is suitable to detect GM2A in samples from Human.

Quick Overview for GM2A antibody (AA 1-193) (ABIN7114727)

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GM2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 9C9

Product Details anti-GM2A Antibody

Binding Specificity: AA 1-193

Purpose: GM2A antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-193aa

Immunogen: GM2 ganglioside activator

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GM2A

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Alternative Name: GM2A

Background:

Synonyms: Ganglioside GM2 activator|Cerebroside sulfate activator protein|GM2-AP|Sphingolipid activator protein 3 (SAP-3)|Ganglioside GM2 activator isoform short|GM2A

Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Molecular Weight: 22 kDa

Gene ID: 2760

UniProt: P17900