GUCA2B antibody

Catalog No. ABIN7114843

This Rabbit Polyclonal antibody specifically detects GUCA2B in ELISA, WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GUCA2B antibody (ABIN7114843)

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA2B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GUCA2B Antibody

Purpose: GUCA2B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: guanylate cyclase activator 2B(uroguanylin)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF:1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GUCA2B

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Alternative Name: GUCA2B

Background:

Synonyms: Guanylate cyclase activator 2B|Guanylate cyclase C-activating peptide 2 Alternative names: Guanylate cyclase C-activating peptide II (GCAP-II)|Uroguanylin (UGN)|GUCA2B

Background: Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension(EH).

Molecular Weight: 12 kDa

Gene ID: 2981

UniProt: Q16661