HEY2 antibody

Catalog No. ABIN7114854

The Rabbit Polyclonal anti-HEY2 antibody (ABIN7114854) specifically detects HEY2 in WB, ELISA, IHC, IF and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HEY2 antibody (ABIN7114854)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-HEY2 Antibody

Purpose: HEY2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: hairy/enhancer-of-split related with YRPW motif 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2

Background:

Synonyms: Hairy/enhancer-of-split related with YRPW motif protein 2|Cardiovascular helix-loop-helix factor 1 (hCHF1)|Class B basic helix-loop-helix protein 32 (bHLHb32)|HES-related repressor protein 2|Hairy and enhancer of split-related protein 2 (HESR-2)|Hairy-related transcription factor 2 (HRT-2, hHRT2)|Protein gridlock homolog|HEY2|BHLHB32|CHF1|GRL|HERP|HERP1|HRT2

Background: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Molecular Weight: 34-36 kDa

Gene ID: 23493

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation