HPS4 antibody

Catalog No. ABIN7114967

The Rabbit Polyclonal anti-HPS4 antibody is suitable to detect HPS4 in samples from Human. It has been validated for WB, IHC, IP, IF and ELISA.

Quick Overview for HPS4 antibody (ABIN7114967)

Target: HPS4 (Hermansky-Pudlak Syndrome 4 (HPS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), ELISA

Product Details anti-HPS4 Antibody

Purpose: HPS4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Hermansky-Pudlak syndrome 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HPS4

Target: HPS4 (Hermansky-Pudlak Syndrome 4 (HPS4))

Alternative Name: HPS4

Background:

Synonyms: BLOC-3 complex member HPS4|Hermansky-Pudlak syndrome 4 protein|Light-ear protein homolog|HPS4|KIAA1667

Background: Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).

Molecular Weight: 70 kDa and 90 kDa

Gene ID: 89781

UniProt: Q9NQG7