AGFG1 antibody

Catalog No. ABIN7115063

The Rabbit Polyclonal anti-AGFG1 antibody is suitable to detect AGFG1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IP.

Quick Overview for AGFG1 antibody (ABIN7115063)

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-AGFG1 Antibody

Purpose: AGFG1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ArfGAP with FG repeats 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Alternative Name: AGFG1

Background:

Synonyms: Arf-GAP domain and FG repeat-containing protein 1|HIV-1 Rev-binding protein|Nucleoporin-like protein RIP|Rev-interacting protein|Rev/Rex activation domain-binding protein|AGFG1|HRB|RAB|RIP

Background: Required for vesicle docking or fusion during acrosome biogenesis(By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Molecular Weight: 58 kDa

Gene ID: 3267

UniProt: P52594