Six5 antibody

Catalog No. ABIN7115099

The Rabbit Polyclonal anti-Six5 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect Six5 in samples from Human.

Quick Overview for Six5 antibody (ABIN7115099)

Target: Six5 (SIX5) (Homeobox protein SIX5 (SIX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Six5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-Six5 Antibody

Purpose: SIX5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SIX homeobox 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Six5

Target: Six5 (SIX5) (Homeobox protein SIX5 (SIX5))

Alternative Name: SIX5

Background:

Synonyms: Homeobox protein SIX5|DM locus-associated homeodomain protein|Sine oculis homeobox homolog 5|SIX5|DMAHP

Background: Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter(By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3(By similarity).

Molecular Weight: 100-105 kDa

Gene ID: 147912

UniProt: Q8N196